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        Bcl-2 Mouse mAb
        EM1041
        規格: 價格:
        50 μl ¥1280.00
        100 μl ¥1980.00

        Overview

        Product name: Bcl-2 Mouse mAb
        Human Swiss-Prot No.: P10415
        Reactivity: Human, Rat, Mouse
        Alternative Names: B-Cell Leukemia/Lymphoma 2 ;B-Cell CLL/Lymphoma 2
        Source: Mouse
        Applications : WB, IHC, IF
        Species reactivity: Human, Rat, Mouse
        Species: Human
        Recommended dilutions: WB 1:1,000-2,000 IHC 1:200 IF 1:100-200
        Immunogen: Synthetic Peptide
        Storage: PBS with 0.02% sodium azide and 50% glycerol pH 7.4. Store at -20°C. Avoid?repeated?freeze-thaw?cycles.
        Clonality: Monoclonal
        Isotype: IgG1
        Concentration: 1mg/ml
        Observed band: 26kDa
        GeneID(Human): 596
        Cellular localization: Mitochondrion outer membrane,Nucleus membrane,Endoplasmic reticulum membrane
        Background: BCL2 is an integral outer mitochondrial membrane protein that blocks the apoptotic death of some cells such as lymphocytes. Constitutive expression of BCL2, such as in the case of translocation of BCL2 to Ig heavy chain locus, is thought to be the cause of follicular lymphoma. BCL2 suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. It regulates cell death by controlling the mitochondrial membrane permeability.
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