| Product name: |
Recombinant 2019-nCoV 3C-like Proteinase (N-6His) |
| Description: |
Recombinant 2019-nCoV 3C-like Proteinase is produced by our E.coli expression system and the target gene encoding Ser1-Gln306 is expressed with a 6His tag at the N-terminus. |
| Expression Host: |
E.coli |
| Accession: |
YP_009725301.1 |
| Molecular weight: |
36.1 KDa |
| Apparent molecular weight: |
33 KDa, reducing conditions |
| Other names: |
M Proteinase; 3CL Proteinase |
| FORMULATION: |
Supplied as a 0.2 μm filtered solution of PBS, 1mM EDTA, 10% Glycerol, pH 7.4. |
| Purity: |
Greater than 95% as determined by reducing SDS-PAGE. |
| Storage: |
Store at ≤-70°C, stable for 6 months after receipt.
Store at ≤-70°C, stable for 3 months under sterile conditions after opening.
Please minimize freeze-thaw cycles. |
| Delivery condition: |
The product is shipped on dry ice/polar packs.
Upon receipt, store it immediately at the temperature listed below. |
| Background: |
The viral main proteinase (M pro , also called 3CL pro ), which controls the activities of the coronavirus replication complex. It functions as a cysteine protease engaging in the proteolytic cleavage of the viral precursor polyprotein to a series of functional proteins required for coronavirus replication and is considered as an appealing target for designing anti-SARS agents. |
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